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System Biology


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Systems biology uses algorithms to measure body system balance in a holistic “real-life” forecast. We measure six Systems key to fertility health.​

The core issue for women with Hot PFPs is they feel warmer than most other people, and they also tend to be ‘on the go’ type of people who find it difficult to relax and put their feet up at the end of the day. Their lack of heat is often a reflection of slower or lower body processes (the metabolic rate) than average. Hot PFPs are the natural opposite of Cold PFPs, who have lower or slower fertility metabolism, and a temperature profile somewhere in the middle is the ideal.

Being mammals, we’re all relatively warm, but some of us are warmer than others. The extra heat can be specific to parts of the body or in general. Temperatures can vary around the body, especially across the lower back, and it’s worth feeling for temperature differences in your lower abdomen, middle and chest. Our temperature varies depending on:

  • Heat levels generated within cells
  • Blood circulation
  • Exposure to heat and cold
  • Sex and hormone levels
  • Diet
  • Exercise
  • Drugs
  • Our age
  • Times of day
  • Infections and inflammation

Because the lower abdomen is where our reproductive organs are, the temperature here is more important than the other parts of the body. Abnormal temperature patterns are the main issues restricting Hot and Cold PFPs’ fertility, and the PFPs can develop differently, which is helpful to know when trying to raise fertility.

Find out if your Hot

It’s easiest to explain these differences using the terms “Full” and “Empty”:

  • Full refers to an excess (usually coming from outside) that increases temperature, and examples are meningitis or sunstroke!
  • Empty refers to a lack of coolness (always internal) that causes a relative excess of heat, and menopausal flushes from lower sex hormones are a classic example.

“Full Hot”

Full Hot is relatively simple to explain, as something from outside the body is warming it up. Infections by viruses or bacteria are the usual causes, but burns are another option, and the heat they bring can directly affect fertility. Sexually transmitted infections such as Chlamydia and Gonorrhoea can generate enough heat to distort and block Fallopian tubes, preventing any chance of natural pregnancy.

Having mumps in adulthood is one example where the swelling and heat in the testes can make men sterile. Sexually transmitted infections such as Chlamydia and Gonorrhoea can also affect a man’s tubes and glands, blocking the flow of semen and lowering sperm health.

However, anything that causes inflammation is heating, and allergies, hyper-sensitivities and autoimmune diseases have heating elements that change fertility levels. The signs of Full Hot are usually fairly straightforward, as they appear reasonably quickly with redness, an aversion to heat, sensations of heat, more thirst, and often irritability.


“Empty Hot”

Empty Hot is more subtle, as it develops when the body isn’t cool enough, so it also usually develops gradually, without an obvious cause, until a point arrives when the extra warmth becomes noticeable. The excess heat tends to be most evident at the end of the day or when over-tired. When people lack heat, they feel cold, and when they lack coolness, they’ll feel hot.

While menopausal flushing isn’t due to infections, they’re not the only time people get night sweats and flushes, as many men experience them. Sex hormone changes are one reason for Empty Hot, but so are other hormone imbalances, and there are also non-hormonal reasons too!

The body can become over-reactive to a standard stimulus simply because it’s run-down, which can become complicated if an altered immune system needs calming down! The best way to reduce inflammation is by reducing exposure to the irritant and supporting coolness in the body.

Reducing exposure and generally cooling the body can make the immune system feel less “threatened” and reactive, so the excess heat gradually fades

Heat is by its very nature agitating, and when there’s excess heat, it increases the chances of anxiety and disturbed sleep. Sleep disturbances affect the ANS and hormone balance, but thankfully, this usually improves when people:

  • Rest more
  • Make specific diet changes
  • Take cooling herbal combinations
  • Use self-help techniques

Hot PFP and Male Fertility

Being too hot is a significant problem for men as very few sperm that grow above the normal scrotal temperature can fertilise an egg. These sperm also have higher DNA fragmentation rates and are less likely to form viable pregnancies. A healthy balance between the immune and nervous systems is essential for general health and crucial for male fertility. The focus for men with Hot PFPs is reducing inflammation, hormonal imbalances and oxidative stress to improve sperm health and DNA integrity.

Morefertile and Hot PFP Men

The morefertile member package has PFP extensions with personalised advice on:

  1. Diet
  2. Healing the gut
  3. Lifestyle and Exercise
  4. Weight
  5. Coping with stress
  6. Appropriate tests and treatments

They also have the most up-to-date research for specific conditions and access to cutting-edge functional medicine tests and personalised herbal combinations. The morefertile approach:

  • Informs and empowers you with focused changes to raise fertility
  • Uncovers and addresses hidden problems
  • Raises general and fertility health
  • Speeds up natural conception times
  • Improves IVF success rates
  • Increases resilience and lowers stress levels