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System Biology


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Systems biology uses algorithms to measure body system balance in a holistic “real-life” forecast. We measure six Systems key to fertility health.​

The core issue for women with Hot PFPs is they feel warmer than most other people, and they also tend to be ‘on the go’ type of people who find it difficult to relax and put their feet up at the end of the day. Their lack of heat is often a reflection of slower or lower body processes (the metabolic rate) than average. Hot PFPs are the natural opposite of Cold PFPs, who have lower or slower fertility metabolism, and a temperature profile somewhere in the middle is the ideal.

Being mammals, we’re all relatively warm, but some of us are warmer than others, and the extra heat can be in parts of the body or in general. Temperatures can vary around the body, especially across the lower back, and it’s worth feeling for temperature differences in your lower abdomen, middle and chest. Our temperature varies depending on:

  • Heat levels generated within cells
  • Blood circulation
  • Exposure to heat and cold
  • Sex and hormone levels
  • Diet
  • Exercise
  • Drugs
  • Our age
  • Times of day
  • Infections and inflammation

Because the lower abdomen is where our reproductive organs are, the temperature here is more important than the other parts of the body. Abnormal temperature patterns are the main issues restricting Hot and Cold PFPs’ fertility, and the PFPs can develop differently, which is useful to know when trying to raise fertility.

Variations of Hot

It’s easiest to explain these differences using the terms “Full” and “Empty”:

Full refers to an excess (usually coming from outside) that increases temperature, and examples are meningitis or sunstroke!
Empty refers to a lack of coolness (always internal) that causes a relative excess of heat, and menopausal flushes from lower sex hormones is a classic example.

“Full Hot”

Full Hot is relatively simple to explain, as something from outside the body warms it up. Infections by viruses or bacteria are the usual causes, but burns are another option, and the heat that they bring can directly affect fertility. Sexually transmitted infections such as Chlamydia and Gonorrhoea can generate enough heat to distort and block Fallopian tubes, preventing any chance of natural pregnancy.

However, anything that causes inflammation is heating, and allergies, hyper-sensitivities and autoimmune diseases have heating elements to them and they change fertility levels. The signs of Full Hot are usually fairly straightforward, and they appear reasonably quickly with redness, an aversion to heat, sensations of heat, more thirst, and often irritability.

“Empty Hot”

Empty Hot is more subtle, as it develops when the body isn’t cool enough, so it also usually develops gradually, without an obvious cause, until a point arrives when the extra warmth becomes noticeable. The extra heat tends to be most evident at the end of the day or when over-tired. When people lack heat, they feel cold, and when they lack coolness, they’ll feel hot.

While menopausal flushing isn’t due to infections, they’re not the only time people get night sweats and flushes as many men experience them too! Sex hormone changes are one reason for Empty Hot, but so are other hormone imbalances, and there are also non-hormonal reasons too! The body can become over-reactive to a standard stimulus simply because it’s run-down, which can become complicated if an altered immune system needs calming!

Reducing exposure and generally cooling the body can make the immune system feel less “threatened” and reactive, so the excess heat gradually fades. A less aggressive can be crucial to the chances of successful implantation and pregnancy.

Hot PFP and Female Fertility

A healthy immune and nervous system balance is essential for a woman’s general health and fertility. The extra heat tends to accelerate and disrupt the menstrual cycle of Hot PFP women, and also reduces cooler aspects of fertility, such as the depth of the womb lining and quantity of fertile mucus.

Inflammation can distort delicate Fallopian tubes, shift the hormonal balance and raise oxidative stress levels, which compromise fertility and vitality.

Identifying what’s heating Hot PFP women and making adjustments to support their constitution and improve egg health is crucial. A “batch” of eggs are recruited each cycle from the ovarian reserve:

  • It usually takes 13 months for eggs to reach the ovulation stage
  • Most of them fail to complete the journey
  • Fewer and fewer reach the final stage as women age
  • Low mature egg numbers indicate lower reserves and more oxidative stress damage
  • It’s possible to reduce FSH levels and damage to eggs with focused changes
  • Herbal combinations are 3x more successful than IVF for unexplained infertility

Morefertile and Hot PFP Women

The morefertile member package has PFP extensions with personalised advice on:

  • Diet
  • Lifestyle
  • Coping with stress
  • Appropriate tests and treatments

They also have the most up-to-date research for specific conditions and access to cutting-edge functional medicine tests and personalised herbal combinations. The morefertile approach:

  • Informs and empowers you with focused changes to raise fertility
  • Uncovers and addresses hidden problems
  • Raises general and fertility health
  • Speeds up natural conception times
  • Improves IVF success rates
  • Increases resilience and lowers stress levels